products

 / healthcare / Haelium™ Lutidine 500

Haelium™ Lutidine 500

critical TIDES manufacturing reagent with lowest residual impurities and water content


  • Haelium™ Lutidine 500 (also known as 2,6-dimethylpyridine) is a critical reagent for TIDES manufacturing, featuring the market's lowest residual impurities and water content <100 ppm for exceptional color stability.
  • Primarily used as a mild, non-nucleophilic base in the "capping" step of oligonu-cleotide synthesis, it's also a versatile solvent and base for other API and chemi-cal manufacturing processes.
  • Its non-nucleophilic character and high solubility in various solvents enable chemoselective transformations economically and on-scale.
  • Manufactured at Aurorium’s US-based sites like Zeeland, Michigan and Pasade-na, Texas.
  • As part of the Haelium™ reagent line, Lutidine 500 offers best-in-class impurity profiles, contributing to higher coupling efficiency and fewer side reactions.



markets served